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Tamar Meyer
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Feb 09, 2010 (11:30 AM)
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Posts:
40
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Mar 03, 2009
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Hi Shannon,
OBJECTIVES: To ascertain the impact of NRT on in-hospital mortality following coronary artery bypass graft (CABG) surgery.
METHODS: This was a retrospective matched cohort pilot studyin a 22-bed cardiothoracic surgery ICU. Patients prescribed transdermal NRT after CABG were randomly selected and matched to current smokers not prescribed NRT according to Acute Physiology and Chronic Health Evaluation II scores (N = 134). Data on comorbid conditions and pack-year history were also obtained. To compare these patients with nonsmoking patients, a larger unmatched population was also evaluated. The total number of patients prescribed NRT, current smokers not prescribed NRT, and nonsmokers who were evaluated in our study was 2057.
CONCLUSIONS: The use of NRT in a postoperative CABG surgery population resulted in a significant increase in mortality when adjusted for baseline characteristics. Patients receiving NRT after off-pump cardiac surgery may be particularly susceptible. Additional evaluation in large patient cohorts with prospective controlsis warranted
Tamar Meyer
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sefurey
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Feb 02, 2010 (10:23 AM)
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Jun 25, 2009
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I was wondering if anyone has research to share on the use of nicotine replacement therapy in the surgical population? I work with a team of surgeons who are concerned about using NRT for patients who have had micro-vascular surgery. Comments?
Shannon
shannon.furey@sunnybrook.ca
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Claudia Mariano
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Feb 01, 2010 (09:02 PM)
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2
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Jan 20, 2010
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I took a quick glance at the guidelines for combining smoking cessation therapies, and was pleased to see the recommendation for combining NRT and zyban. As we heard at the conference last week, the issues of combining NRT with other therapies is problematic for health care providers, due to the restrictions in the product monographs. The dissemination of these guidelines will go a long way to reassure practitioners. Hopefully we can see similar guidelines for champix in the future.
Claudia Mariano
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